Patients with rheumatoid arthritis presenting with mono- or oligo-arthritis and high Visual Analogue Scale (VAS)-ratings remain the most fatigued during 5 years of follow-up
Main finding · Fatigue over time (VAS, mm)Result — go to the resultDifference +20 mmAuthors' conclusion
The RA patients who remain the most fatigued were those characterized by mono- or oligo-arthritis and high PGA (VAS ≥ 50) at diagnosis.
Study context
- Population
- Early RA patients in the Leiden Early Arthritis Cohort and the tREACH trial1,560 Leiden + 415 tREACH
- Exposure
- DAS components at diagnosis in relation to course of fatigue
- Outcome
- Course of fatigue (VAS, 0-100 mm)
- Follow-up
- 5 years
Methodological detailstwo independent early RA cohorts, linear mixed models
- Two independent early RA cohorts
- Linear mixed models
Main finding
Fatigue over time (VAS, mm)
Difference
+20 mm
As reported in the abstract
- Subgroup (mono-/oligo-arthritis and Patient Global Assessment (PGA) ≥ 50) proportion of early RA population
- 14%
Observational data: associations, not effects.
Further findings
Replication in tREACH trial
- Similar findings
Original publication
Patients with rheumatoid arthritis presenting with mono- or oligo-arthritis and high VAS-ratings remain the most fatigued during 5 years of follow-up. Rheumatology (Oxford). Published 26 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →