Revisiting idiopathic eosinophilic myositis: towards a clinical-pathological continuum from the muscle to the fascia and skin
Authors' conclusion
The analysis of IEM and EF patient characteristics delineates four subgroups (FEM, DEM, EMF and EF) in terms of clinical, laboratory, imaging, pathological and outcome specificities
Study context
- Population
- Idiopathic eosinophilic myositis (IEM) patients diagnosed 2000–2022 (eosinophilic muscle infiltration with myositis pathological features, differential diagnoses excluded) and EF patients diagnosed 2016–202220 IEM and 10 EF cases
- Participants
- 3 / 6 / 11 / 10
- Exposure
- Focal EM (FEM) vs diffuse EM (DEM) vs eosinophilic myofasciitis (EMF) vs EF
- FEMn = 3
- DEMn = 6
- EMFn = 11
- EFn = 10
- Outcome
- Clinical-pathological subgroups of idiopathic eosinophil muscle infiltration
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
| Outcome | EMF | EF |
|---|---|---|
| Myalgia | 55% | 50% |
| Hypereosinophilia | 55% | — not stated in the abstract |
| Fascia-restricted infiltrates with eosinophils | — not stated in the abstract | 60% |
| Fascia-restricted infiltrates without eosinophils | — not stated in the abstract | 40% |
— not stated in the abstract
- Age at diagnosis, median (IQR), years
- 65 (49-70)
- Males
- 18
Observational data: associations, not effects.
Original publication
Revisiting idiopathic eosinophilic myositis: towards a clinical-pathological continuum from the muscle to the fascia and skin. Rheumatology (Oxford). Published 6 October 2022. doi:10.
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