Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study
Authors' conclusion
This population-based study found that DM incidence and prevalence were higher than previously reported. Mortality was significantly elevated for myopathic DM but not for CADM.
Study context
- Population
- Incident dermatomyositis (DM) meeting EULAR/American College of Rheumatology (ACR) criteria, Olmsted County, 1995–201929 incident cases
- Participants
- 40 participants
- Exposure
- Myopathic DM vs clinically amyopathic DM (CADM)
- CADMn = 12
- Outcome
- Incidence, prevalence and mortality of DM (EULAR/ACR criteria)
Methodological detailsmanual record review, age- and sex-adjusted to US non-Hispanic White 2000 population
- Manual record review
- Age- and sex-adjusted to US non-Hispanic White 2000 population
Main finding
As reported in the abstract
Incidence, prevalence and mortality of DM
Adjusted incidence of DM, per 100,000 person-years
1.1
95% CI 0.7–1.5
Prevalence of DM, per 100,000
13
95% CI 6–19
SMR, myopathic DM (95% CI 1.1-6.8); significantly elevated
3.1
SMR, CADM (95% CI 0.2-3.3); not significantly elevated
1.1
Observational data: associations, not effects.
Further findings
- PPV of ≥2 DM codes, 40 of 82
- 49%
Original publication
Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study. Arthritis Care Res (Hoboken). Published 6 October 2022. doi:10. 1002/ acr. 24786
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