Inflammatory myopathies

Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study

Arthritis Care Res (Hoboken)Published Population-based cohort study

Authors' conclusion

This population-based study found that DM incidence and prevalence were higher than previously reported. Mortality was significantly elevated for myopathic DM but not for CADM.

Study context

Population
Incident dermatomyositis (DM) meeting EULAR/American College of Rheumatology (ACR) criteria, Olmsted County, 1995–201929 incident cases
Participants
40 participants
Exposure
Myopathic DM vs clinically amyopathic DM (CADM)
  • CADMn = 12
Outcome
Incidence, prevalence and mortality of DM (EULAR/ACR criteria)
Methodological detailsmanual record review, age- and sex-adjusted to US non-Hispanic White 2000 population
  • Manual record review
  • Age- and sex-adjusted to US non-Hispanic White 2000 population

Main finding

As reported in the abstract

Incidence, prevalence and mortality of DM

Adjusted incidence of DM, per 100,000 person-years

1.1

95% CI 0.7–1.5

Prevalence of DM, per 100,000

13

95% CI 6–19

SMR, myopathic DM (95% CI 1.1-6.8); significantly elevated

3.1

SMR, CADM (95% CI 0.2-3.3); not significantly elevated

1.1

Observational data: associations, not effects.

Further findings

PPV of ≥2 DM codes, 40 of 82
49%

Original publication

Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study. Arthritis Care Res (Hoboken). Published 6 October 2022. doi:10.1002/acr.24786

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