Lupus & antiphospholipid syndrome
Retrospective cohort study identifying pulmonary complications in a cohort of patients with systemic lupus erythematosus
Authors' conclusion
While our study is limited by the retrospective nature, our results show that certain factors, namely smoking, older age, or male sex should prompt clinicians to have a higher suspicion for lung disease in SLE patients.
Study context
- Population
- Adults (>18 years) with systemic lupus erythematosus (SLE) confirmed by a rheumatologist (SLICC or 2019 ACR/EULAR criteria) with imaging; mean age 42.5 years, 86.7% femalepatients with imaging
- Participants
- 220 adults
- Outcome
- Pulmonary manifestations on CT and chest X-ray and associated risk factors
Methodological detailselectronic health record data, generalized estimating equations
- Electronic health record data
- Generalized estimating equations
Main finding
As reported in the abstract
Factors associated with pulmonary disease on imaging
- Smoking (present/prior) associated with radiologist-reported disease on computerized tomography (CT)
- Smoking (present/prior), older age and male sex associated with pulmonary disease on chest X-ray
Observational data: associations, not effects.
Further findings
Most common findings on CT and X-ray
- Increased lung density (CT, X-ray)
- 24%, 12%
- Atelectasis (CT, X-ray)
- 18%, 10%
Most common disease on CT
- Pleural effusion
- 24%
- Mediastinal/axillary lymphadenopathy
- 16%
Original publication
Retrospective cohort study identifying pulmonary complications in a cohort of patients with systemic lupus erythematosus. Lupus. Published 12 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →