Systemic sclerosis & Raynaud's

Results from the international collaborative systematic literature review informing the 2023 EULAR recommendations for the treatment of systemic sclerosis

Ann Rheum DisPublished Systematic literature review

Authors' conclusion

This SLR provides and summarises the highest level of evidence for the new EULAR recommendations for the treatment of SSc, providing an unprecedented comprehensive overview of recent knowledge on SSc treatments and participating in defining the future research agenda.

Study context

Population
Literature on treatment of systemic sclerosis (SSc) (30 searches for 30 interventions, plus 1 dedicated search for calcinosis)483 full texts evaluated
Outcome
Literature retrieved and included, and question types covered
Methodological detailsinternational collaborative, informing EULAR recommendations for SSc treatment
  • International collaborative
  • Informing EULAR recommendations for SSc treatment

Main finding

As reported in the abstract

Abstracts retrieved on 31 March 2022
14 490
Abstracts retrieved on 11 October 2022
2021
New full texts evaluated
483
New articles included, first search
172
New articles included, second search
9
Type III questions (new interventions)
40%
Type II questions (new outcomes)
26%

Original publication

Results from the international collaborative systematic literature review informing the 2023 EULAR recommendations for the treatment of systemic sclerosis. Ann Rheum Dis. Published 2 January 2025. doi:10.1136/ard-2024-226429

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