Lupus & antiphospholipid syndrome
Systematic literature review informing the EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus and systemic sclerosis
Authors' conclusion
In summary, non-pharmacological management of SLE and SSc encompasses a wide range of interventions, which can be combined and provided either with or without adjunct pharmacological treatment but should not aim to substitute the latter when this is deemed required.
Study context
- Population
- Studies of non-pharmacological management of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) published between January 2000 and June 2021articles included
- Participants
- 208 participants
Methodological detailsinforming EULAR recommendations, thematic categorisation by intervention, critical appraisal
- Informing EULAR recommendations
- Thematic categorisation by intervention
- Critical appraisal
Main finding
As reported in the abstract
- Physical activity: most studied strategy, efficacious in both SLE and SSc
- Patient education and self-management: widely studied topics
- SLE: many studies found psychological interventions improve quality of life
- SSc: phototherapy and laser treatment improved cutaneous disease manifestations
- 118 studies for SLE and 92 for SSc selected for data extraction
- 51 articles classified as robust in critical appraisal
Original publication
Systematic literature review informing the EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus and systemic sclerosis. RMD Open. Published 2 August 2023. doi:10.
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