Lupus & antiphospholipid syndrome
Results and prognosis of kidney transplantation in lupus nephritis: Experience of an Argentine center
Authors' conclusion
Patients transplanted for LN did not differ from the control population in terms of graft and patient survival.
Study context
- Population
- Kidney transplant recipients with ESRD due to LN or other causes, single Argentine center
- Participants
- 41 vs 89
- Exposure
- Kidney transplantation for LN vs kidney transplantation for other causes of ESRD
- LNn = 41
- Other causesn = 89reference
- Outcome
- Graft loss
Methodological detailsobservational, analytical, single-centre
- Observational
- Analytical
- Single-centre
Main finding
As reported in the abstract
P = 0.428
Observational data: associations, not effects.
Further findings
| Outcome | LN | P value |
|---|---|---|
| Patient deathLN vs Comparison group | 19.5% | P = 0.42 |
| Graft survival by aPL status (sub-analysis)Positive aFL vs Negative aFL | P = 0.96 |
- Reactivation of LN in the graft
- 4.8% · 1
- Mortality by aPL status (sub-analysis) · Positive aFL vs Negative aFL
- P = 0.61
- Patient death: Comparison group 12.4%
- Graft survival by aPL status (sub-analysis): Positive aFL 75.7 months
- Graft survival by aPL status (sub-analysis): Negative aFL 72.7 months
Patient death
- Infections were the main cause of death in both groups
Graft survival by aPL status (sub-analysis)
- No significant differences in causes of graft loss and graft survival
Mortality by aPL status (sub-analysis)
- No differences in mortality between the groups
Safety
| Outcome | Values |
|---|---|
| Thrombotic events in aPL-positive LN patients | aPL-positive 4 events |
- Thrombotic events in aPL-positive LN patients: in 3 different patients
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Results and prognosis of kidney transplantation in lupus nephritis: Experience of an Argentine center. Lupus. Published 3 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →