Lupus & antiphospholipid syndrome
Referral and evaluation for kidney transplantation among patients with lupus nephritis-related end-stage kidney disease
Authors' conclusion
Among incident patients with ESKD, having a primary diagnosis of LN-ESKD versus other-ESKD is associated with higher rates of early transplant access outcomes.
Study context
- Population
- Adults who began treatment for ESKD in the Southeast, Northeast, New York or Ohio River Valley US regions, 1/1/2012–12/31/2019, followed through 6/30/2021; referral and evaluation data from 28 of 48 transplant centers0.4% LN-ESKD
- Participants
- 192,318 adults
- Exposure
- LN-ESKD vs other-ESKD
- Outcome
- Referral and evaluation start at a transplant center
Methodological detailsregistry-based (United States Renal Data System), Cox models, adjusted analyses
- Registry-based (United States Renal Data System)
- Cox models
- Adjusted analyses
Main finding
As reported in the abstract
LN-ESKD vs Other-ESKDHazard ratio (95% CI)
Referral; adjusted
1.09(0.99–1.19)
Evaluation start; adjusted
1.13(1.00–1.28)
- LN-ESKD referred before study end
- 58%
- LN-ESKD referred who started evaluation
- 66%
Observational data: associations, not effects.
Further findings
Time from ESKD start to referral (referred patients)
Time from ESKD start to referral (referred patients)
- Similar between groups
Original publication
Referral and evaluation for kidney transplantation among patients with lupus nephritis-related end-stage kidney disease. Lupus. Published 29 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →