Responders to Medial Opening Wedge High Tibial Osteotomy for Knee Osteoarthritis
Authors' conclusion
Based on responder criteria for knee OA, 78% of patients undergoing medial opening wedge HTO were responders at 2 years postsurgery.
Study context
- Population
- Patients with symptomatic knee osteoarthritis (OA) and varus alignment undergoing medial opening wedge high tibial osteotomy (HTO)
- Participants
- 405 vs 118
- Exposure
- Male vs Female
- Malen = 405
- Femalen = 118
- Outcome
- Proportion of OMERACT-OARSI responders: ≥ 20% relative improvement and absolute change of ≥ 10 points in KOOS pain and function from baseline
- Follow-up
- 2 years
Methodological detailslogistic regression, sex-disaggregated analyses
- Logistic regression
- Sex-disaggregated analyses
Main finding
As reported in the abstract
OMERACT-OARSI responders · mean 20.3 (SD 6.2) months post-HTO
Patients meeting responder criteria
406
78%
Observational data: associations, not effects.
Further findings
Responders by sex
Predictors of response
- Older age, higher BMI and larger postoperative mechanical axis angles (slight valgus) associated with increased odds of response, although ORs were small
Original publication
Responders to Medial Opening Wedge High Tibial Osteotomy for Knee Osteoarthritis. J Rheumatol. Published 15 February 2023. doi:10.
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