Osteoarthritis

Magnetic resonance imaging (MRI) underestimates presence and size of knee osteophytes using computed tomography (CT) as a reference standard

Osteoarthritis CartilagePublished Diagnostic accuracy study

Authors' conclusion

MRI underestimates presence of osteophytes in all three knee compartments.

Study context

Population
Patients with primary knee OA in the SEKOIA trial with available MRI and CT data (mean age 62.9 ± 7.5 years)1,332 locations evaluated
Participants
74 patients
Comparison
MRI vs CT for knee osteophytes
Outcome
Diagnostic performance of MRI for osteophytes in all three knee compartments (PFJ, medial TFJ, lateral TFJ), CT as reference
Follow-up
Baseline
Methodological detailssecondary analysis of SEKOIA trial baseline data, CT as reference standard, modified MRI Osteoarthritis Knee Score (MOAKS) scoring
  • Secondary analysis of SEKOIA trial baseline data
  • CT as reference standard
  • Modified MOAKS scoring

Performance

As reported in the abstract

Osteophytes detected by MRI among CT-defined osteophytes, by compartment

PFJ: MRI detected 141 (72%) of 197 CT-defined osteophytes (OPs); w-kappa

0.58 (0.52-0.65) (95% CI)

Medial TFJ: MRI detected 178 (81%) of 219 CT-OPs; w-kappa

0.58 (0.51-0.64) (95% CI)

Lateral TFJ: MRI detected 84 (70%) of 120 CT-OPs; w-kappa

0.58 (0.50-0.66) (95% CI)

Original publication

MRI underestimates presence and size of knee osteophytes using CT as a reference standard. Osteoarthritis Cartilage. Published 14 February 2023. doi:10.1016/j.joca.2023.01.575

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