Spondyloarthritis & psoriatic arthritis
Relationship between ultrasound damage score of peripheral entheses and spinal bone formation in long-standing radiographic axial spondyloarthritis
Main findingResult — go to the resultRate ratio for log-transformed mSASSS+1, adjusted for symptom duration 1.32 95% CI 1.04–1.67Authors' conclusion
Structural lesions at the peripheral entheses are common in long-standing r-axSpA and accumulate with age, which may obscure the possible association with spinal bone formation.
Study context
- Population
- Patients with long-standing radiographic axial spondyloarthritis (r-axSpA) fulfilling the modified New York criteria for ankylosing spondylitis (AS) (mean age 55 years; symptom duration 29 years)54% males
- Participants
- 173 patients
- Exposure
- Association between ultrasound (US) damage score of peripheral entheses and modified Stoke AS Spinal Score (mSASSS), overall, by sex and by age quartiles
- Outcome
- Association between US damage score (0-42) and spinal bone formation (mSASSS)
Methodological detailsnegative binomial regression
- Negative binomial regression
Main finding
As reported in the abstract
Rate ratio for log-transformed mSASSS+1, adjusted for symptom duration
1.32
95% CI 1.04–1.67
Malesvs Females
rate ratio for log-transformed mSASSS+1, adjusted for symptom duration 1.32 (95% CI 1.04–1.67)
Observational data: associations, not effects.
Further findings
Mean
| Outcome | Males | Females | P value |
|---|---|---|---|
| US damage score by sex | 4.7 (SD 3.0) | 3.3 (SD 2.4) | P < 0.001 |
Prevalence of any structural US lesion
- Any structural US lesion
- 92%
US damage score by sex
- US damage score and mSASSS increased significantly with age
Original publication
Relationship between ultrasound damage score of peripheral entheses and spinal bone formation in long-standing radiographic axial spondyloarthritis. RMD Open. Published 4 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →