Spondyloarthritis & psoriatic arthritis
Relationship between spinal structural damage and sagittal balance in axial spondyloarthritis: Is the thoracic spine the starting point?
Authors' conclusion
Our data showed that more spinal structural damage is associated with a higher SVA, reflecting poorer sagittal balance.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA)
- Participants
- 107 patients
- Exposure
- Modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) tertile groups: G2 and G3 vs G1
- G1n = 36reference
- G2n = 36
- G3n = 35
- Outcome
- Relationship between spinal structural damage (mSASSS) and sagittal balance (SVA) and spine curvatures
Methodological detailsEOS® imaging, multivariable regression analysis
- EOS® imaging
- Multivariable regression analysis
Main finding
As reported in the abstract
SVA
P < 0.001
- Multivariable regression: one-unit increase in total mSASSS associated with average higher sagittal vertical axis (SVA)
- 0.8 mm
Observational data: associations, not effects.
Further findings
Thoracic kyphosis T1-T12 — G2 and G3 vs G1 · higher in G2 and G3
P < 0.001
Lumbar L1-S1 lordosis (straightening in G3) — G3 vs G1 and G2 · lumbar straightening in G3
P < 0.001
Original publication
Relationship between spinal structural damage and sagittal balance in axial spondyloarthritis: Is the thoracic spine the starting point? Semin Arthritis Rheum. Published 7 February 2024. doi:10. 1016/ j. semarthrit. 2024. 152415
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