Spondyloarthritis & psoriatic arthritis

Relationship between spinal structural damage and sagittal balance in axial spondyloarthritis: Is the thoracic spine the starting point?

Semin Arthritis RheumPublished Cross-sectional study

Authors' conclusion

Our data showed that more spinal structural damage is associated with a higher SVA, reflecting poorer sagittal balance.

Study context

Population
Patients with axial spondyloarthritis (axSpA)
Participants
107 patients
Exposure
Modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) tertile groups: G2 and G3 vs G1
  • G1n = 36reference
  • G2n = 36
  • G3n = 35
Outcome
Relationship between spinal structural damage (mSASSS) and sagittal balance (SVA) and spine curvatures
Methodological detailsEOS® imaging, multivariable regression analysis
  • EOS® imaging
  • Multivariable regression analysis

Main finding

As reported in the abstract

SVA

P < 0.001

Multivariable regression: one-unit increase in total mSASSS associated with average higher sagittal vertical axis (SVA)
0.8 mm

Observational data: associations, not effects.

Further findings

Thoracic kyphosis T1-T12 — G2 and G3 vs G1 · higher in G2 and G3

P < 0.001

Lumbar L1-S1 lordosis (straightening in G3) — G3 vs G1 and G2 · lumbar straightening in G3

P < 0.001

Original publication

Relationship between spinal structural damage and sagittal balance in axial spondyloarthritis: Is the thoracic spine the starting point? Semin Arthritis Rheum. Published 7 February 2024. doi:10.1016/j.semarthrit.2024.152415

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