Spondyloarthritis & psoriatic arthritis

Redundant radiography before CT in axial spondyloarthritis: high radiation burden, limited diagnostic value

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

In CT-confirmed r-axSpA, multiple radiographs are frequently obtained before definitive imaging, adding substantial radiation without improving diagnostic yield, whereas a single appropriately indicated low-dose CT could achieve structural assessment with less redundant exposure.

Study context

Population
Patients with sacroiliac CT-confirmed radiographic axial SpA (r-axSpA) who had pelvic and lumbar radiographs before CT235 radiographs before CT
Exposure
Cumulative radiographic dose before CT vs hypothetical single low-dose CT (0.5 mSv) or conventional CT (4-10 mSv)
Outcome
Number and cumulative radiation dose of pelvic and lumbar radiographs obtained before sacroiliac CT-confirmed diagnosis of r-axSpA
Methodological detailsinstitutional and national databases, hypothetical dose scenarios, paired Wilcoxon signed-rank tests
  • Institutional and national databases
  • Hypothetical dose scenarios
  • Paired Wilcoxon signed-rank tests

Main finding

As reported in the abstract

Radiographs performed before CT
235
Radiographs per patient, mean (range 0-8)
2.47
Patients with ≥2 combined radiographs
77.9%
Under minimum assumptions, radiographic exposure similar to low-dose CT
P = 0.307
Under maximum assumptions, exposure markedly higher than low-dose CT (median difference)
+2.30 mSv, P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeMinimum scenarioMaximum scenario
Patients exceeding a fixed 4.0 mSv conventional CT benchmark0 events7.4%

Patients with cumulative X-ray dose ≥0.5 mSv

Under minimum assumptions
10.5%
Under maximum assumptions
82.1%

Original publication

Redundant radiography before CT in axial spondyloarthritis: high radiation burden, limited diagnostic value. Rheumatology (Oxford). Published 3 February 2026. doi:10.1093/rheumatology/keag066

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