Spondyloarthritis & psoriatic arthritis
Assessment of enthesopathy in conventional pelvis radiography: Another tool for spondyloarthritis diagnosis beyond sacroiliitis
Authors' conclusion
The assessment of pelvic enthesis using the REI on pelvic radiography may be useful for SpA diagnosis. Total REI, ZIII, and ZI had the highest accuracy and almost perfect reliability.
Study context
- Population
- Spondylarthritis (SpA) patients and controls with chronic lumbar pain without SpA
- Participants
- 161 patients
- Comparison
- Radiographic enthesis index (REI) on pelvic X-ray vs sacroiliitis on X-ray for SpA diagnosis
- SpAn = 111
- Controlsn = 50reference
- Outcome
- Association of pelvic enthesis involvement on pelvic X-ray (REI) with SpA diagnosis; reliability and accuracy of the REI
Methodological detailsblinded observers, case-control (SpA vs chronic lumbar pain controls), Three blinded observers assessed each pelvic radiograph three times; weighted kappa adjusted with Gwet's agreement coefficient
- Blinded observers
- Case-control (SpA vs chronic lumbar pain controls)
- Three blinded observers assessed each pelvic radiograph three times; weighted kappa adjusted with Gwet's agreement coefficient
Performance
As reported in the abstract
Sensitivity for SpA diagnosis
| Test or model | Value | Sensitivity |
|---|---|---|
| REI | 82 % | 82 % |
| Sacroiliitis on X-ray | 38.7 % | 38.7 % |
Value
REI82 %
Sacroiliitis on X-ray38.7 %
Sensitivity
REI82 %
Sacroiliitis on X-ray38.7 %
Further findings
REI Grades 1 to 3 in ZI (iliopubic ramus)
Grade 1 SpA 8.1 %
Grade 2 SpA 14.4 %
Grade 3 SpA 19.8 %
ZII (pubic symphysis) unaffected
| Outcome | SpA | Controls |
|---|---|---|
| REI Grades 2 and 3 in ZIII (ischiopubic ramus) | 36.7 % and 25.7 % | 6 % |
| Grade 2 | 36.7 % | — not stated in the abstract |
| Grade 3 | 25.7 % | — not stated in the abstract |
— not stated in the abstract
- REI-positive among SpA patients without sacroiliitis on X-ray
- 75 %
Original publication
Assessment of enthesopathy in conventional pelvis radiography: Another tool for spondyloarthritis diagnosis beyond sacroiliitis. Semin Arthritis Rheum. Published 4 April 2024. doi:10. 1016/ j. semarthrit. 2024. 152435
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