Lupus & antiphospholipid syndrome

Racial differences in medication beliefs and adherence barriers among patients with systemic lupus erythematosus

LupusPublished Cross-sectional study

Authors' conclusion

Nonadherence among Black patients was uniquely associated with stronger concerns about medication overuse and harm and weaker beliefs that SLE medicines were necessary, potentially reflecting medical mistrust that may drive skipping doses when feeling well or when concerns arise.

Study context

Population
Black and White patients with systemic lupus erythematosus (SLE) who completed the Beliefs about Medicines Questionnaire and the SLE-specific Domains of Subjective Extent of Nonadherence survey52% Black, 48% White
Participants
123 participants
Exposure
Black vs White patients with SLE
Outcome
Medication adherence

Main finding

As reported in the abstract

P = 0.02

Observational data: associations, not effects.

Further findings

Medication beliefs by race

Black patients reported greater concerns about SLE medications and medication overuse and harm than White patients

Medication beliefs by adherence among Black patients

Nonadherent Black patients reported weaker beliefs in SLE medication necessity and greater concerns about medication overuse and harm than adherent Black patients

Reasons for nonadherence reported by Black but not White patients

Feeling well
45%
Concerns about future fertility
14%
Doubts about their doctors and medicines
8%

Original publication

Racial differences in medication beliefs and adherence barriers among patients with systemic lupus erythematosus. Lupus. Published 1 December 2025. doi:10.1177/09612033251406326

Composed by AI from the published abstract and checked against it. How Briefs are made →

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