Lupus & antiphospholipid syndrome
Differences in Self-Reported Medication Nonadherence and Its Drivers in Young Adults Versus Older Adults With Systemic Lupus Erythematosus
Authors' conclusion
Younger patients reported greater extent of nonadherence, often due to logistical impediments.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) completing the DOSE-Nonadherence-SLE questionnaire, February 2020 to June 2024
- Participants
- 336 surveys
- Exposure
- Medication nonadherence across age groups
- Outcome
- Rate of self-reported medication nonadherence by age and reasons for nonadherence
Methodological detailssurvey (DOSE-Nonadherence-SLE questionnaire), logistic regression
- Survey (DOSE-Nonadherence-SLE questionnaire)
- Logistic regression
Main finding
As reported in the abstract
Medication nonadherence across age groups
- Nonadherence differed significantly across age groups 18-29, 30-39, 40-49 and 50+
- P < 0.001
- Self-reported nonadherence decrease per each increased year of age
- 2% (P < 0.05)
Observational data: associations, not effects.
Further findings
Reasons for nonadherence, < 30 age group
| OR (95% CI) | ||
|---|---|---|
| < 30Inability to fill medications on time | 3.72 (1.53–9.02) | |
| < 30Needing to take medicines with food | 2.55 (1.06–6.13) | |
| 0.10.31310Odds ratio (log scale) |
Predictors of nonadherence across age groups
- Black race and Hispanic ethnicity also predictive of nonadherence
Original publication
Differences in Self-Reported Medication Nonadherence and Its Drivers in Young Adults Versus Older Adults With Systemic Lupus Erythematosus. J Rheumatol. Published 1 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →