Lupus & antiphospholipid syndrome
Treatment adherence and quality of life in colombian patients with lupus nephritis
Authors' conclusion
LupusQoL pain domain scores were significantly worse in non-adherent patients compared to adherent patients.
Study context
- Population
- Patients with biopsy-proven lupus nephritis (LN) from the Colombian Caribbean, June–December 202238 (90%) female
- Participants
- 42 patients
- Exposure
- Non-adherent vs adherent patients with LN
- Non-adherentn = 25
- Outcome
- Relationship between health-related quality of life (HRQoL) (LupusQoL) and treatment adherence (CQR19)
Methodological detailsprincipal component analysis
- Principal component analysis
Main finding
As reported in the abstract
LupusQoL pain domain score
- Non-adherent vs Adherent: P < 0.05
Observational data: associations, not effects.
Further findings
Correlations of Lupus Quality of Life (LupusQoL) domains
- Poorer planning score vs older age (r)
- −0.72
- Poorer planning score vs longer disease duration (r)
- −0.74
- SLEDAI-2 K vs pain domain (r)
- −0.78
- Each p < .05
LupusQoL domains overall
- Pain, planning and intimate relationships domains unaffected; burden to others domain lowest score
- Principal component analysis (PCA): strong interactions between planning and pain, and between physical health and body image
Original publication
Treatment adherence and quality of life in colombian patients with lupus nephritis. Lupus. Published 26 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →