Lupus & antiphospholipid syndrome
Quality of life, fatigue, sleep quality, and mental health in systemic lupus erythematosus patients with a high cardiovascular risk profile
Authors' conclusion
Despite similar HRQL, fatigue, and sleep quality parameters to those reported by other SLE populations, SLE patients with a high cardiovascular risk had a higher prevalence of depression and anxiety.
Study context
- Population
- Systemic lupus erythematosus (SLE) patients with a high cardiovascular risk profile (BMI 25–40 kg/m² and/or dyslipidemia, hypertension, or diabetes); mean age 41.7 ± 9 years; 87% overweight/obese87 assessed for sleep quality
- Participants
- 100 patients
- Outcome
- Health-related quality of life (HRQL), fatigue, anxiety and depression symptoms, and sleep quality
Main finding
As reported in the abstract
HRQL, fatigue, anxiety/depression and sleep quality
- SF-36 physical component summary
- 51.3 ± 9.6
- SF-36 mental component summary
- 54.2 ± 15.6
- Total SLEQOL score
- 105.1 ± 42.0
- Fatigue score
- 30.8 ± 8.9
- Severe anxiety symptoms
- 78%
- Severe depression symptoms
- 93%
- Sleep effectiveness
- 82.9 ± 6.6%
- Sleep latency (min)
- 8.4 ± 8.9
- Total time in bed (min)
- 495.8 ± 79.7
- Total sleep time (min)
- 409.7 ± 69.9
- Wake episodes (WE)
- 17.8 ± 6.2
- WE duration (min)
- 4.5 ± 1.5
- WASO (min)
- 77.7 ± 36.6
Observational data: associations, not effects.
Original publication
Quality of life, fatigue, sleep quality, and mental health in systemic lupus erythematosus patients with a high cardiovascular risk profile. Lupus. Published 12 September 2023. doi:10.
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