Lupus & antiphospholipid syndrome
Prognostic value and predictors of the alteration of the diffusing capacity of the lungs for carbon monoxide in systemic lupus erythematosus
Authors' conclusion
This study suggests a link between DLCO alteration and disease damage, potentially related to SLE vasculopathy, and a prognostic value of DLCO on death or intensive care unit admission in SLE.
Study context
- Population
- SLE patients fulfilling the 2019 EULAR/ACR classification criteria, DLCO measured in routine follow-up
- Participants
- 232 patients
- Outcome
- DLCO alteration (<70% of predicted value), its predictors and prognostic value
- Follow-up
- End
Main finding
As reported in the abstract
DLCO alteration (<70% of predicted value) at least once
Patients with DLCO alteration
154
66.4%
Observational data: associations, not effects.
Original publication
Prognostic value and predictors of the alteration of the diffusing capacity of the lungs for carbon monoxide in systemic lupus erythematosus. Rheumatology (Oxford). Published 13 October 2023. doi:10.
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