Spondyloarthritis & psoriatic arthritis

Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

There is a significant hidden disease burden of axSpA among IBD patients.

Study context

Population
Consecutive patients attending IBD clinics in a university teaching hospital with self-reported chronic back pain >3 months, onset <45 years, 18–80 years old, biologic therapy naive, no previous diagnosis of axSpAeligible for clinical assessment
Participants
82 patients
Outcome
Prevalence of undiagnosed rheumatology-verified axSpA (RVD-axSpA)
Methodological detailssecondary care, single-centre, Of 470 patients approached, 91 had self-reported chronic back pain (CBP) >3 months, onset <45 years, Rheumatology assessment: medical review, physical examination, PROMs, HLA-B27, CRP, pelvic radiograph and axSpA protocol MRI; diagnosis by a panel of rheumatologists
  • Secondary care
  • Single-centre
  • Of 470 patients approached, 91 had self-reported CBP >3 months, onset <45 years
  • Rheumatology assessment: medical review, physical examination, PROMs, HLA-B27, CRP, pelvic radiograph and axSpA protocol MRI; diagnosis by a panel of rheumatologists

Main finding

As reported in the abstract

Prevalence of undiagnosed RVD-axSpA

Prevalence of undiagnosed rheumatology-verified diagnosis of axial spondyloarthritis (RVD-axSpA)

5%

95% CI 1.3, 12.0

Mean symptom duration, years (s.d. 12.4)

12

Observational data: associations, not effects.

Original publication

Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study. Rheumatology (Oxford). Published 22 August 2022. doi:10.1093/rheumatology/keac473

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