Spondyloarthritis & psoriatic arthritis
Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study
Authors' conclusion
There is a significant hidden disease burden of axSpA among IBD patients.
Study context
- Population
- Consecutive patients attending IBD clinics in a university teaching hospital with self-reported chronic back pain >3 months, onset <45 years, 18–80 years old, biologic therapy naive, no previous diagnosis of axSpAeligible for clinical assessment
- Participants
- 82 patients
- Outcome
- Prevalence of undiagnosed rheumatology-verified axSpA (RVD-axSpA)
Methodological detailssecondary care, single-centre, Of 470 patients approached, 91 had self-reported chronic back pain (CBP) >3 months, onset <45 years, Rheumatology assessment: medical review, physical examination, PROMs, HLA-B27, CRP, pelvic radiograph and axSpA protocol MRI; diagnosis by a panel of rheumatologists
- Secondary care
- Single-centre
- Of 470 patients approached, 91 had self-reported CBP >3 months, onset <45 years
- Rheumatology assessment: medical review, physical examination, PROMs, HLA-B27, CRP, pelvic radiograph and axSpA protocol MRI; diagnosis by a panel of rheumatologists
Main finding
As reported in the abstract
Prevalence of undiagnosed RVD-axSpA
Prevalence of undiagnosed rheumatology-verified diagnosis of axial spondyloarthritis (RVD-axSpA)
5%
95% CI 1.3, 12.0
Mean symptom duration, years (s.d. 12.4)
12
Observational data: associations, not effects.
Original publication
Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study. Rheumatology (Oxford). Published 22 August 2022. doi:10. 1093/ rheumatology/ keac473
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