Spondyloarthritis & psoriatic arthritis

Women With Psoriatic Arthritis Experience Higher Disease Burden Than Men: Findings From a Real-World Survey in the United States and Europe

J RheumatolPublished Cross-sectional study

Authors' conclusion

In patients with similar PsA disease activity and treatment, women experienced greater disease impact than men.

Study context

Population
Patients with psoriatic arthritis (PsA) of rheumatologists/dermatologists in France, Germany, Italy, Spain, the UK and the US, June–August 2018 (mean age 48.6 yrs; mean disease duration 4.9 yrs)1,047 (46.1%) women
Participants
2,270 patients
Exposure
Women vs men with PsA
  • Womenn = 1,047
Outcome
QOL (EQ-5D), mean, women vs men
Methodological detailsreal-world survey, multinational, Survey conducted June–August 2018
  • Real-world survey
  • Multinational
  • Survey conducted June–August 2018

Main finding

As reported in the abstract

Women

0.80

SD 0.2

Men

0.82

SD 0.2

P = 0.02

Observational data: associations, not effects.

Further findings

OutcomeWomenMenP value
Disability (HAQ-DI)0.56 (SD 0.6)0.41 (SD 0.5)P < 0.01
Work activity impairment (WPAI)27.9% (SD 22.0)24.6% (SD 22.4)P < 0.01
Comorbidity burden (Charlson Comorbidity Index)Lower in women1.10 (SD 0.5)1.15 (SD 0.6)P < 0.01
Quality of life (QOL) (EQ-5D)
P = 0.02

Disease duration, disease presentation and biologic use

Comparable between women and men (biologic use mean 54.2%)

Original publication

Women With Psoriatic Arthritis Experience Higher Disease Burden Than Men: Findings From a Real-World Survey in the United States and Europe. J Rheumatol. Published 15 August 2022. doi:10.3899/jrheum.220154

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