Spondyloarthritis & psoriatic arthritis
Comparing MRI and conventional radiography for the detection of structural changes indicative of axial spondyloarthritis in the ASAS cohort
Authors' conclusion
Structural lesions of the SI joint detected by MRI demonstrated better diagnostic performance and better interreader reliability compared with conventional radiography.
Study context
- Population
- Adult patients from the ASAS cohort with symptoms suggestive of axial spondyloarthritis (axSpA) and both SI joint MRI and radiographs available for central reading135 (73.7%) diagnosed with axSpA
- Participants
- 183 patients
- Comparison
- SI joint MRI vs conventional radiography for structural lesions, vs rheumatologist's diagnosis of axSpA
- Outcome
- Diagnostic performance (sensitivity, specificity, PPV, NPV, LR+, LR-) vs rheumatologist's diagnosis of axSpA
Methodological detailscentral reading
- Central reading
Performance
As reported in the abstract
Diagnostic performance vs rheumatologist's diagnosis of axSpA
| Test or model | Sensitivity | Specificity | PPV | NPV | LR+ | LR- |
|---|---|---|---|---|---|---|
| MRI structural lesions | 38.5% | 91.7% | 92.9% | 34.6% | 4.62 | 0.67 |
| Modified New York (mNY) sacroiliitis | 54.8% | 70.8% | 84.1% | 35.8% | 1.88 | 0.64 |
| Sacroiliitis ≥ grade 2 unilaterally | 65.2% | 50.0% | 78.6% | 33.8% | 1.30 | 0.69 |
Sensitivity
MRI structural lesions38.5%
Modified New York (mNY) sacroiliitis54.8%
Sacroiliitis ≥ grade 2 unilaterally65.2%
Specificity
MRI structural lesions91.7%
Modified New York (mNY) sacroiliitis70.8%
Sacroiliitis ≥ grade 2 unilaterally50.0%
PPV
MRI structural lesions92.9%
Modified New York (mNY) sacroiliitis84.1%
Sacroiliitis ≥ grade 2 unilaterally78.6%
NPV
MRI structural lesions34.6%
Modified New York (mNY) sacroiliitis35.8%
Sacroiliitis ≥ grade 2 unilaterally33.8%
LR+
MRI structural lesions4.62
Modified New York (mNY) sacroiliitis1.88
Sacroiliitis ≥ grade 2 unilaterally1.30
LR-
MRI structural lesions0.67
Modified New York (mNY) sacroiliitis0.64
Sacroiliitis ≥ grade 2 unilaterally0.69
Original publication
Comparing MRI and conventional radiography for the detection of structural changes indicative of axial spondyloarthritis in the ASAS cohort. Rheumatology (Oxford). Published 11 August 2022. doi:10.
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