Spondyloarthritis & psoriatic arthritis
Impact of Physician-Defined Flares on Quality of Life and Work Impairment: An International Survey of 2238 Patients With Psoriatic Arthritis
Authors' conclusion
Actively experiencing a flare adversely affected QOL, disability, and work productivity.
Study context
- Population
- Patients with psoriatic arthritis (PsA) managed by rheumatologists/dermatologists in France, Germany, Italy, Spain, the UK and the US572 physicians
- Participants
- 2,238 patients
- Exposure
- Patients by flare status: currently flaring vs not flared in last 12 months or never flared
- Outcome
- PsA flares and their effect on patient-reported outcomes (PROs) (EQ-5D-5L, WPAI, HAQ-DI, PsAID-12)
Methodological detailsinternational survey, physician and patient surveys, multivariate logistic regression adjusted for patient demographics and physician specialty
- International survey
- Physician and patient surveys
- Multivariate logistic regression adjusted for patient demographics and physician specialty
Main finding
As reported in the abstract
PROs by flare status
- No flare in last 12 months or never flared: higher QOL, lower overall work impairment and lower disability vs current flare
- all; P < 0.01
- Physician-reported flare
- 168 patients (7.5%)
- Self-reported flare
- 95 patients (10% of available data)
- Flare count over 12 months, mean (SD)
- 2.2 (4.9)
- Flare duration, mean (SD), days
- 16.4 (16.2)
Observational data: associations, not effects.
Original publication
Impact of Physician-Defined Flares on Quality of Life and Work Impairment: An International Survey of 2238 Patients With Psoriatic Arthritis. J Rheumatol. Published 15 August 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →