Rheumatoid arthritis

Prevalence of coeliac disease in patients with rheumatoid arthritis and juvenile idiopathic arthritis: a systematic review and meta-analysis

Clin Exp RheumatolPublished Systematic review and meta-analysis

Authors' conclusion

In this meta-analysis, we found a pooled prevalence of biopsy-confirmed CD in patients with RA and JIA comparable to that in the general population.

Study context

Population
Patients with Rheumatoid Arthritis (RA) and Juvenile Idiopathic Arthritis (JIA); studies in Medline, Embase, Cochrane and Web of Science Core Collection, 1 January 1990 to 31 October 20229 RA and 18 JIA studies in primary analyses
Participants
754 vs 2,077
Comparison
RA vs JIA
  • RAn = 754
  • JIAn = 2,077
Outcome
Prevalence of biopsy-confirmed coeliac disease
Methodological detailsmeta-regression
  • Meta-regression

Pooled result

As reported in the abstract

Biopsy-confirmed coeliac disease, weighted pooled prevalence

Further pooled results

OutcomeRAJIA
Positive coeliac disease serology, pooled prevalence0.9% (95% CI 0.3–1.9)5.4% (95% CI 2.5–9.2)

Original publication

Prevalence of coeliac disease in patients with rheumatoid arthritis and juvenile idiopathic arthritis: a systematic review and meta-analysis. Clin Exp Rheumatol. Published 26 April 2023. doi:10.55563/clinexprheumatol/b92b8a

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