Lupus & antiphospholipid syndrome

Prevalence and incidence of systemic lupus erythematosus in Thailand based on national health data

Lupus Sci MedPublished Retrospective cohort study

Authors' conclusion

SLE is relatively common in Thailand, particularly among women of reproductive age and residents of the southern region.

Study context

Population
Adults (≥18 years) with a primary diagnosis of SLE (ICD-10 M32), Thai Ministry of Public Health national data covering all major healthcare insurance systems, 2017–2020total Thai population, 2017
Participants
65,204,797 adults
Outcome
Point and period prevalence (per 100 000 population) and annual incidence rates (per 100 000 person-years) of SLE
Methodological detailsnationwide, national health data
  • Nationwide
  • National health data

Main finding

As reported in the abstract

Prevalent SLE cases, 2017
55 956
Point prevalence, 2017
85.8 (per 100 000; 95% CI 85.1 to 86.5)
Incident SLE cases 2018, 2019, 2020
15 403, 16 243 and 15 925
Annual incidence rates 2018, 2019, 2020 (per 100 000 person-years)
23.6, 24.8 and 24.3
Cumulative incidence over 3 years
72.7 (per 100 000 person-years; 95% CI 72.0 to 73.4)

Observational data: associations, not effects.

Further findings

Prevalence by sex (per 100 000) · 2017

Women vs men
152.9 vs 15.9
Female-to-male ratio
9.6:1

Prevalence by age and region (per 100 000) · 2017

Highest age group, 40-49 years
128.3
Highest region, southern
178.5

Incidence by age and region

Peak incidence at ages 40-49 in 2019 (per 100 000)
33.7
Incidence in the south, 2018-2020 (per 100 000 person-years; consistently highest)
60.0, 53.9 and 57.3

Original publication

Prevalence and incidence of systemic lupus erythematosus in Thailand based on national health data. Lupus Sci Med. Published 4 September 2025. doi:10.1136/lupus-2025-001621

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