Sjögren's disease & overlap diseases
Prevalence and Incidence of Sjögren's Disease in Alaska Native and American Indian Peoples of Alaska
Authors' conclusion
The prevalence and incidence of SjD in AN/AI peoples is higher than other populations.
Study context
- Population
- Adult AN/AI peoples of Alaska in the Alaska Tribal Health System (ATHS), diagnosed with Sjögren's disease (SjD) by a rheumatologist
- Outcome
- Prevalence and incidence of SjD (age-adjusted)
- Follow-up
- 2019 (point prevalence); 2012 to 2019 (incidence)
Methodological detailsprevalence and incidence, electronic health record query, medical record abstraction, direct age adjustment to the 2000 standard US population
- Prevalence and incidence
- Electronic health record query
- Medical record abstraction
- Direct age adjustment to the 2000 standard US population
Main finding
As reported in the abstract
SjD, age-adjusted prevalence and incidence
Age-adjusted prevalence of SjD, per 100,000 adults
199
95% CI 170–231
Age-adjusted prevalence of primary SjD, per 100,000 adults (106, 155)
129
Age-adjusted prevalence of secondary SjD, per 100,000 adults
70
95% CI 54–91
Age-adjusted incidence over 2012–2019, per 100,000 person-years
16.6
95% CI 13.7–20.0
Observational data: associations, not effects.
Further findings
Classification criteria and biopsy
- Met modified criteria (positive Ro/SSA with sicca symptoms)
- 66%
- Salivary gland biopsy performed
- 5%
- Met 2016 American College of Rheumatology (ACR)/EULAR or 2012 ACR criteria
- 3%
Associated conditions in secondary SjD
- Most common: RA and SLE
Original publication
Prevalence and Incidence of Sjögren's Disease in Alaska Native and American Indian Peoples of Alaska. Arthritis Care Res (Hoboken). Published 15 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →