Lupus & antiphospholipid syndrome

Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lupus erythematosus

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

In SLE patients with clinically active joints, US-proven enthesitis is a fairly common finding.

Study context

Population
SLE patients (EULAR/ACR criteria) with tender and/or swollen joints undergoing articular US, Lupus Unit, Careggi University Hospital106 underwent articular US
Participants
400 patients
Exposure
SLE with US-proven enthesitis vs SLE controls without US evidence of enthesitis
  • Enthesitisn = 31
  • Controlsn = 71reference
Outcome
Prevalence of US-confirmed enthesitis
Methodological detailscase-control comparison, single-centre, Four controls excluded due to lack of follow-up data
  • Case-control comparison
  • Single-centre
  • Four controls excluded due to lack of follow-up data

Main finding

As reported in the abstract

US-confirmed enthesitis among patients examined with articular US

Enthesitis

29.2%

31

Observational data: associations, not effects.

Further findings

Follow-up duration

Renal involvement during follow-up

P = 0.028

Failure of B cell depletion

Laboratory and clinical features at disease onset

Comparable between cases and controls

Original publication

Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lupus erythematosus. Rheumatology (Oxford). Published 17 March 2023. doi:10.1093/rheumatology/kead123

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