Lupus & antiphospholipid syndrome
Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lupus erythematosus
Authors' conclusion
In SLE patients with clinically active joints, US-proven enthesitis is a fairly common finding.
Study context
- Population
- SLE patients (EULAR/ACR criteria) with tender and/or swollen joints undergoing articular US, Lupus Unit, Careggi University Hospital106 underwent articular US
- Participants
- 400 patients
- Exposure
- SLE with US-proven enthesitis vs SLE controls without US evidence of enthesitis
- Enthesitisn = 31
- Controlsn = 71reference
- Outcome
- Prevalence of US-confirmed enthesitis
Methodological detailscase-control comparison, single-centre, Four controls excluded due to lack of follow-up data
- Case-control comparison
- Single-centre
- Four controls excluded due to lack of follow-up data
Main finding
As reported in the abstract
US-confirmed enthesitis among patients examined with articular US
Enthesitis
29.2%
31
Observational data: associations, not effects.
Further findings
Follow-up duration
Renal involvement during follow-up
P = 0.028
Failure of B cell depletion
Laboratory and clinical features at disease onset
- Comparable between cases and controls
Original publication
Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lupus erythematosus. Rheumatology (Oxford). Published 17 March 2023. doi:10. 1093/ rheumatology/ kead123
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