Presence of periodontal disease and the incidence of inflammatory arthritides in the general population: data from the UK Biobank
Authors' conclusion
Self-reported periodontal disease is associated with inflammatory arthritides incidence in participants included in the UK Biobank, particularly for RA and AS.
Study context
- Population
- UK Biobank participants without a previous history of RA, AS and PsA
- Participants
- 489,125 participants
- Exposure
- Periodontal disease vs no periodontal disease
- Periodontal diseasen = 86,905
- Without periodontal diseasen = 402,220reference
- Outcome
- Incidence of inflammatory arthritides (composite of RA, AS and PsA)
Methodological detailsmultivariate Cox proportional hazard regression (four models)
- Multivariate Cox proportional hazard regression (four models)
Main finding
As reported in the abstract
Composite inflammatory arthritides
- Periodontal disease an independent predictor of composite inflammatory arthritides; consistent in the four Cox models and with different definitions of periodontal disease
Observational data: associations, not effects.
Further findings
RA and AS
- Association also consistent for RA and AS
RA, subgroups
- Increased RA risk in those aged <60 years; persistent for male and female patients and for seropositive/seronegative RA
Original publication
Presence of periodontal disease and the incidence of inflammatory arthritides in the general population: data from the UK Biobank. Rheumatology (Oxford). Published 12 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →