Elevated triglyceride levels are associated with increased risk for major adverse cardiovascular events in statin-naïve rheumatoid arthritis patients: A nationwide cohort study
Authors' conclusion
In statin-naïve RA patients, increased TG level is associated with increased risk for MACE.
Study context
- Population
- Statin-naïve rheumatoid arthritis (RA) patients with no previous history of cardiovascular eventsmedian follow-up 4.70 years
- Participants
- 15,216 patients
- Exposure
- Baseline triglyceride (TG) quartiles
- Outcome
- Composite MACE:
- Myocardial infarction (MI)
- Stroke
- Coronary revascularization
- Cardiovascular death
Main finding
As reported in the abstract
Composite MACE by baseline TG quartile
Adjusted hazard ratio (95% CI)
TG Q3vs TG Q1 (lowest)
1.35(1.03–1.78)
TG Q4 (highest)vs TG Q1 (lowest)
1.74(1.33–2.28)
Observational data: associations, not effects.
Further findings
Incidence of MACE per 1000 person-years (overall cohort) · median 4.70 years
- Incidence of MACE per 1000 person-years
- 7.27
Original publication
Elevated triglyceride levels are associated with increased risk for major adverse cardiovascular events in statin-naïve rheumatoid arthritis patients: A nationwide cohort study. Semin Arthritis Rheum. Published 5 October 2023. doi:10.
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