Vasculitis & polymyalgia rheumatica
Predictors of post-operative cardiovascular complications for Behçet's disease with pre-operative immunosuppressive therapy
Authors' conclusion
Pre-operative immunosuppressive therapy is vital for BD patients.
Study context
- Population
- Behçet's disease (BD) patients who underwent cardiovascular surgery with perioperative immunosuppressive therapy, Guangdong Provincial People's Hospital, 2012 to 2024
- Exposure
- Pre-operative immunosuppressive therapy vs none
- Outcome
- Post-operative complications
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
In-hospital complications
P < 0.001
Observational data: associations, not effects.
Further findings
Independent factors for post-operative complications
| HR (95% CI) | P value | ||
|---|---|---|---|
| RF | 1.088 (0.998–1.187) | P = 0.056 | |
| PLR | 1.004 (1.000–1.008) | P = 0.075 | |
| NLR | 1.065 (1.002–1.133) | P = 0.045 | |
| 0.512Hazard ratio (log scale) |
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Independent factors for post-operative complicationsPre-operative immunosuppressive therapyvs No pre-operative immunosuppressive therapyProtective factor | 0.206 (0.061–0.693) | P = 0.011 | |
| 0.050.21520Hazard ratio (log scale) |
ROC for four or more positive biomarkers
- AUC
- 0.849
Original publication
Predictors of post-operative cardiovascular complications for Behçet's disease with pre-operative immunosuppressive therapy. Clin Exp Rheumatol. Published 23 October 2025. doi:10.
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