Vasculitis & polymyalgia rheumatica
Vascular uptake on 18F-FDG PET/CT predicts relapse in new-onset PMR
Main finding · Relapse rateResult — go to the resultHazard ratio 3.731 95% CI 1.705–8.164Authors' conclusion
Our findings highlight vascular involvement as a critical predictor of relapse in PMR, underscoring the utility of 18F-FDG PET/CT in detecting subclinical GCA and predicting prognosis.
Study context
- Population
- Patients diagnosed with PMR who underwent PET/CT at Ruijin hospital, September 2015 to December 2023
- Participants
- 80 patients
- Exposure
- PMR with vascular involvement on 18F-FDG PET/CT vs without
- Subclinical GCAn = 14
- Outcome
- Relapse
Methodological detailssingle-centre, multivariate Cox regression
- Single-centre
- Multivariate Cox regression
Main finding
Relapse rate
Hazard ratio
3.731
95% CI 1.705–8.164
By group
Subclinical GCAvs Isolated PMR
HR 3.731 (95% CI 1.705–8.164)
As reported in the abstract
Observational data: associations, not effects.
Further findings
- Subclinical GCA prevalence
- 17.5% · 14
- Subclinical GCA prevalence — Extracranial vessel involvement among subclinical GCA (13/14)
- 93%
Arthralgia as predictor of relapse (protective)
- HR
- 0.325 (95% CI 0.148-0.711)
Original publication
Vascular uptake on 18F-FDG PET/CT predicts relapse in new-onset PMR. Rheumatology (Oxford). Published 23 October 2025. doi:10.
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