Spondyloarthritis & psoriatic arthritis
Prediction of the activity of early ankylosing spondylitis using radiomics texture analysis on short tau inversion recovery (STIR)
Authors' conclusion
Radiomics analysis based on STIR texture analysis has a good prediction for the evaluation of bone marrow oedema activity of sacroiliac joints in AS.
Study context
- Population
- Patients with early AS; sacroiliac joint bone marrow oedema, active vs stabletraining n=116, validation n=56
- Participants
- 43 patients
- Comparison
- Radscore vs SPARCC vs ADC for differentiating active vs stable sacroiliac joint bone marrow oedema
- Outcome
- AUC for differentiating active vs stable sacroiliac joint bone marrow oedema
Methodological detailsradiomics texture analysis, training and validation cohorts (7:3)
- Radiomics texture analysis
- Training and validation cohorts (7:3)
Performance
As reported in the abstract
AUC, training cohort
| Test or model | AUC |
|---|---|
| Radscore | 0.81 |
| SPARCC | 0.91 |
| ADC | 0.78 |
AUC
Radscore0.81
SPARCC0.91
ADC0.78
- Radscore vs SPARCC: P > 0.05 — no significant difference, both cohorts
- Radscore vs ADC: P > 0.05 — no significant difference, both cohorts
- SPARCC vs ADC: P < 0.05 — significant difference, training cohort
Further findings
| Outcome | P value |
|---|---|
| AUC for active vs stable sacroiliac joint bone marrow oedema, validation cohortRadscore vs SPARCC | P > 0.05 |
| AUC for active vs stable sacroiliac joint bone marrow oedema, validation cohortSPARCC vs ADC · no statistical significance in the validation cohort | P > 0.05 |
- AUC for active vs stable sacroiliac joint bone marrow oedema, validation cohort — Validation cohort AUCs of Radscore, SPARCC and ADC
- 0.87, 0.89, 0.85
- AUC for active vs stable sacroiliac joint bone marrow oedema, validation cohort: no significant differences in AUCs between Radscore and SPARCC, ADC in the two cohorts
Correlation of Radscore with ESR, CRP, tI, ASDAS-ESR and ASDAS-CRP
- Correlations all low
- P < 0.05
- Spearman correlation
Original publication
Prediction of the activity of early ankylosing spondylitis using radiomics texture analysis on STIR. Clin Exp Rheumatol. Published 26 October 2023. doi:10.
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