Spondyloarthritis & psoriatic arthritis

Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis

RMD OpenPublished Diagnostic accuracy study

Authors' conclusion

The high consistency of the scoring pipeline with human readers suggested that the deep learning-based algorithm has the potential to provide semiquantitative assessment of spinal inflammation based on SPARCC in axial SpA.

Study context

Population
Patients with axSpA undergoing whole spine MRI with STIR at 3T
Participants
330 patients
Comparison
Deep learning-based Spondyloarthritis Research Consortium of Canada (SPARCC) scoring pipeline vs human readers
Outcome
Agreement (ICC) and correlation (Pearson) of SPARCC scores between human readers and deep learning pipeline
Methodological detailsdeep learning (attention Unet), whole spine MRI, STIR, 3T
  • Deep learning (attention Unet)
  • Whole spine MRI, STIR, 3T

Performance

As reported in the abstract

SPARCC scores, human readers vs deep learning pipeline

Intraclass correlation coefficient (ICC)

0.80

Pearson coefficient

0.82

Further findings

OutcomeDeep learning pipeline
Spinal inflammation identification (BMO model)
Sensitivity0.90
Specificity0.84

Localisation in images with spinal inflammation (VB-IVD model), Dice coefficient

Dice coefficient, vertebral body (VB)
0.81
Dice coefficient, intervertebral disc (IVD)
0.80

Original publication

Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis. RMD Open. Published 16 January 2026. doi:10.1136/rmdopen-2025-006403

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