Spondyloarthritis & psoriatic arthritis
Pre-eclampsia is more common in women with active psoriatic arthritis in pregnancy: a population-based study
Main finding · Pre-eclampsiaResult — go to the resultRisk difference 6.1 % 95% CI 0.3–20.3Authors' conclusion
Hypertensive disorders of pregnancy occurred more often in women with active, but not inactive PsA. We found no increased risk for preterm birth or abnormal fetal growth in women with PsA.
Study context
- Population
- Singleton births in women with psoriatic arthritis (PsA) with available disease activity assessment, RevNatus 2010 to 2019, Norway109 PsA cases
- Participants
- 34 / 75 / 575,798
- Exposure
- Active PsA and inactive PsA in pregnancy vs population controls
- Active PsAn = 34
- Inactive PsAn = 75
- Population controlsn = 575,798reference
- Outcome
- Pre-eclampsia, gestational hypertension, preterm birth and fetal growth by peripheral disease activity
Methodological detailsnationwide register linkage (RevNatus and Medical Birth Registry of Norway (MBRN)), population controls
- Nationwide register linkage (RevNatus and MBRN)
- Population controls
Main finding
Pre-eclampsia
Risk difference
6.1 %
95% CI 0.3–20.3
P = 0.036
Events by group
Active PsAvs Population controls
risk difference 6.1 % (95% CI 0.3–20.3); P = 0.036
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Active PsA | Inactive PsA | Population controls | Risk difference (%) (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Gestational hypertensionActive PsAvs Population controls | 5.9% | 2.7% | 1.7% | 4.2 (0.0–17.4) | P = 0.065 | |
| −1001020Difference, % (linear scale) |
| Outcome | P value |
|---|---|
| Gestational hypertensionInactive PsA vs Population controls · similar proportions | P = 0.24 |
Preterm birth and abnormal fetal growth
- Comparable in cases and population controls
Original publication
Pre-eclampsia is more common in women with active psoriatic arthritis in pregnancy: a population-based study. RMD Open. Published 28 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →