Spondyloarthritis & psoriatic arthritis

Impact of Social Factors on Visual Analog Scale Pain in Patients With Spondyloarthritis: A Propensity Score Matching Analysis

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Main finding · VAS pain, matched sampleResult — go to the resultAverage treatment effect on the treated +0.38 VAS points 95% CI 0.05–0.71

Authors' conclusion

Social disadvantage, summarized by the SFI, is independently associated with greater pain severity in spondyloarthritis after adjustment.

Study context

Population
Patients with SpA from REGISPONSER and RESPONDIAmean 745 matched pairs · REGISPONSER 1,514 · RESPONDIA 528
Participants
2,042 patients
Exposure
Highest vs lowest Social Factors Index quartile
Outcome
Patient-reported pain severity on VAS
Methodological detailspropensity-score matched, 1:1 caliper matching (0.2 SD on the logit), multiple imputation (m = 20)
  • Propensity-score matched
  • 1:1 caliper matching (0.2 SD on the logit)
  • Multiple imputation (m = 20)

Main finding

VAS pain, matched sample

Average treatment effect on the treated

+0.38 VAS points

95% CI 0.05–0.71

P = 0.023

As reported in the abstract

Observational data: associations, not effects.

Further findings

Visual Analog Scale (VAS) pain, postmatching regression

Postmatching regression β (identical estimate to ATT)
+0.37; 95% CI 0.04-0.70; P = 0.030

VAS pain, Spain (stratified analysis)

Spain
+0.31 (95% CI 0.08-0.71)
  • Stratified analyses suggested heterogeneity

VAS pain, Latin America (stratified analysis)

Latin America
+0.62 (95% CI −0.22 to 1.45)
  • Stratified analyses suggested heterogeneity

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Impact of Social Factors on Visual Analog Scale Pain in Patients With Spondyloarthritis: A Propensity Score Matching Analysis. Arthritis Care Res (Hoboken). Published 27 October 2025. doi:10.1002/acr.25675

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