Spondyloarthritis & psoriatic arthritis
Impact of Social Factors on Visual Analog Scale Pain in Patients With Spondyloarthritis: A Propensity Score Matching Analysis
Main finding · VAS pain, matched sampleResult — go to the resultAverage treatment effect on the treated +0.38 VAS points 95% CI 0.05–0.71Authors' conclusion
Social disadvantage, summarized by the SFI, is independently associated with greater pain severity in spondyloarthritis after adjustment.
Study context
- Population
- Patients with SpA from REGISPONSER and RESPONDIAmean 745 matched pairs · REGISPONSER 1,514 · RESPONDIA 528
- Participants
- 2,042 patients
- Exposure
- Highest vs lowest Social Factors Index quartile
- Outcome
- Patient-reported pain severity on VAS
Methodological detailspropensity-score matched, 1:1 caliper matching (0.2 SD on the logit), multiple imputation (m = 20)
- Propensity-score matched
- 1:1 caliper matching (0.2 SD on the logit)
- Multiple imputation (m = 20)
Main finding
VAS pain, matched sample
Average treatment effect on the treated
+0.38 VAS points
95% CI 0.05–0.71
P = 0.023
As reported in the abstract
Observational data: associations, not effects.
Further findings
Visual Analog Scale (VAS) pain, postmatching regression
- Postmatching regression β (identical estimate to ATT)
- +0.37; 95% CI 0.04-0.70; P = 0.030
VAS pain, Spain (stratified analysis)
- Spain
- +0.31 (95% CI 0.08-0.71)
- Stratified analyses suggested heterogeneity
VAS pain, Latin America (stratified analysis)
- Latin America
- +0.62 (95% CI −0.22 to 1.45)
- Stratified analyses suggested heterogeneity
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Impact of Social Factors on Visual Analog Scale Pain in Patients With Spondyloarthritis: A Propensity Score Matching Analysis. Arthritis Care Res (Hoboken). Published 27 October 2025. doi:10. 1002/ acr. 25675
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