Lupus & antiphospholipid syndrome
Post-traumatic stress disorder in patients with systemic lupus erythematosus heavily affects quality of life. A cross-sectional web survey-based study
Authors' conclusion
PTSD is possibly far more frequent in patients with SLE than in general population and exerts a detrimental influence on quality of life.
Study context
- Population
- Patients with Systemic Lupus Erythematosus (SLE) in the authors' cohortcompleted questionnaire
- Participants
- 99 patients
- Exposure
- SLE with Post-traumatic Stress Disorder (PTSD) vs SLE without PTSD
- Outcome
- PTSD prevalence (TALS-SR) and its impact on quality of life (Lupus QoL)
Methodological detailsweb survey-based
- Web survey-based
Main finding
As reported in the abstract
PTSD prevalence (TALS-SR)
Scored Trauma and Loss Spectrum - Self Reported (TALS-SR) consistent with PTSD
31%
Observational data: associations, not effects.
Further findings
| Outcome | PTSD | Without PTSD | P value |
|---|---|---|---|
| Lupus QoL planning domainLower scores with PTSD | 83.3 | 100 | P = 0.035 |
| Lupus QoL body image domainLower scores with PTSD | 85.0 | 95.0 | P = 0.031 |
| Lupus QoL fatigue domainLower scores with PTSD | 66.7 | 91.7 | P = 0.001 |
Fatigue prevalence
- Fatigue prevalence
- 75%
Correlation of TALS-SR domains with Lupus QoL scores
- Inverse correlation, fatigue with reaction to losses or upsetting events (ρ, p < .001)
- −0.458
Original publication
Post-traumatic stress disorder in patients with systemic lupus erythematosus heavily affects quality of life. A cross-sectional web survey-based study. Lupus. Published 14 December 2022. doi:10.
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