Lupus & antiphospholipid syndrome
Posttraumatic Stress Disorder and Risk of Systemic Lupus Erythematosus Among Medicaid Recipients
Main finding · Incident SLE among those with PTSDResult — go to the resultMultivariable-adjusted OR 2.00 95% CI 1.64–2.46Authors' conclusion
In this large, racially and sociodemographically diverse US population, we found patients with a prior PTSD diagnosis had twice the odds of a subsequent diagnosis of SLE.
Study context
- Population
- Medicaid enrollees aged 18–65 years, enrolled ≥12 months, 29 most populated US states, 2007–2010matched 1:10
- Participants
- 10,942 vs 109,420
- Comparison
- Posttraumatic stress disorder (PTSD) vs no PTSD, association with incident systemic lupus erythematosus (SLE)
- SLE casesn = 10,942
- Controlsn = 109,420reference
- Outcome
- Association of PTSD with incident SLE
Methodological detailsmatched 1:10 by age, sex and race, conditional logistic regression
- Matched 1:10 by age, sex and race
- Conditional logistic regression
Main finding
Incident SLE among those with PTSD
Multivariable-adjusted OR
2.00
95% CI 1.64–2.46
PTSDvs No PTSD
multivariable-adjusted OR 2.00 (95% CI 1.64–2.46)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prevalence of PTSD
Original publication
Posttraumatic Stress Disorder and Risk of Systemic Lupus Erythematosus Among Medicaid Recipients. Arthritis Care Res (Hoboken). Published 1 September 2022. doi:10.
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