Lupus & antiphospholipid syndrome
Post-COVID-19 psychological condition in systemic lupus erythematosus patients: a prospective observational study
Authors' conclusion
Our study demonstrated a worse long-term mental status in COVID-19 infected SLE patients.
Study context
- Population
- Systemic lupus erythematosus (SLE) patients
- Participants
- 619 patients
- Exposure
- COVID-19 infected vs uninfected SLE patients
- COVID-19n = 493
- Uninfectedn = 126reference
- Outcome
- Post-COVID-19 psychological condition: pain (visual analogue scale (VAS)), fatigue (MFI), depression (PHQ-9), sleep quality (PSQI)
Methodological detailsnetwork analysis, logistic regression
- Network analysis
- Logistic regression
Main finding
As reported in the abstract
Pain, General Fatigue, PHQ-9 and PSQI ratings
- Higher pain in COVID-19 infected vs others
- p=0.006
- Higher General Fatigue (GF) in COVID-19 infected vs others
- p=0.027
- Higher PHQ-9 in COVID-19 infected vs others
- p=0.003
- Higher Pittsburgh Sleep Quality Index (PSQI) in COVID-19 infected vs others
- p=0.049
Observational data: associations, not effects.
Further findings
Network analysis in infected patients: core symptoms
- GF and 'Feeling down, hopeless' (PHQ2): core symptoms, greatest expected influence
- 1.20
Network analysis in infected patients: bridge symptoms (bridge expected influence)
- 'Trouble sleeping' (PHQ3)
- 0.72
- GF
- 0.56
- 'Daytime dysfunction' (Daytime dysfunction (DD))
- 0.53
COVID-19 symptoms and post-COVID-19 psychological condition
- Shortness of breath, weakness and joint discomfort linked to post-COVID-19 psychological condition
Original publication
Post-COVID-19 psychological condition in systemic lupus erythematosus patients: a prospective observational study. Clin Exp Rheumatol. Published 13 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →