Systemic sclerosis & Raynaud's
Performance of respiratory patient reported outcome instruments in systemic sclerosis associated interstitial lung disease trials: Are we falling at the first hurdle?
Authors' conclusion
The findings of this review highlight the lack of consensus for the use of respiratory-specific PRO instrument use in SSc-ILD RCTs.
Study context
- Population
- SSc-ILD randomised controlled trials (RCTs) using respiratory-specific patient-reported outcome (PRO) instruments17 measurement-property studies
- Outcome
- Respiratory-specific PRO instruments used in SSc-ILD RCTs
Methodological detailsCOSMIN framework and regulatory guidance
- COSMIN framework and regulatory guidance
Pooled result
As reported in the abstract
Respiratory-specific PRO instruments identified
10
Single-item instruments
4
Instruments developed with any interstitial lung disease (ILD) patient input
2
Studies assessing measurement properties in an SSc-ILD population (varying methodologies)
17
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Performance of respiratory patient reported outcome instruments in systemic sclerosis associated interstitial lung disease trials: Are we falling at the first hurdle? Semin Arthritis Rheum. Published 24 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →