Performance of sit-to-stand, timed up-and-go, and six-minute walk tests in home and office settings in patients with idiopathic inflammatory myopathy
Authors' conclusion
STS, TUG and 6MWD have good test-retest reliability, validity and responsiveness. 6MWD has poor reliability when self-performed at home, while STS/TUG perform similarly in the office and home settings.
Study context
- Population
- Adults with idiopathic inflammatory myopathies (IIM) (mean age 51.6, 60% female)24, 23, 20 completed home sit-to-stand (STS), timed-up-and-go (TUG), 6MWD
- Participants
- 50 adults
- Exposure
- Functional tests performed in office vs self-performed at home
- Outcome
- Measurement properties (reliability, validity, responsiveness) of STS, TUG and 6MWD in office and home settings
Methodological detailsmeasurement properties, home and office settings, assessments at 0, 3 and 6 months
- Measurement properties
- Home and office settings
- Assessments at 0, 3 and 6 months
Main finding
As reported in the abstract
Measurement properties of STS, TUG and 6MWD
- STS and TUG showed strong test-retest reliability at both home and office settings
- 6MWD significantly higher in office setting; TUG/STS comparable between home and office
- All three tests significantly discriminated active vs inactive disease
- All three tests had significant cross-sectional and longitudinal association with patient centered outcome measures (PCOMs) of physical function, quality of life and physical activity
Observational data: associations, not effects.
Original publication
Performance of sit-to-stand, timed up-and-go, and six-minute walk tests in home and office settings in patients with idiopathic inflammatory myopathy. Semin Arthritis Rheum. Published 12 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →