Inflammatory myopathies

Toward digitally supported self-assessment of patients with idiopathic inflammatory myopathies

Arthritis Res TherPublished Prospective observational study

Authors' conclusion

Patient-performed functional tests are reliable, scalable alternatives to MMT8, with gait analysis providing complementary insights.

Study context

Population
Patients with idiopathic inflammatory myopathies (IIM)67.9% female
Participants
28 patients
Exposure
Patient-performed functional tests and inertial sensor-based gait analysis vs manual muscle testing (MMT8)
Outcome
Correlation of gait parameters with MMT8
Follow-up
T0
Methodological detailsshared decision-making, inertial sensor-based gait analysis, electronic patient-reported outcomes
  • Shared decision-making
  • Inertial sensor-based gait analysis
  • Electronic patient-reported outcomes

Main finding

As reported in the abstract

Walking speed vs MMT8 (moderate correlation)

r = 0.545

p = 0.004

Stride length vs MMT8 (moderate correlation)

r = 0.580

p = 0.002

Observational data: associations, not effects.

Further findings

Agreement between patient- and healthcare professional (HCP)-recorded functional test results · baseline and 3 months

Excellent agreement (ICC)
0.99-1.00

Correlation of functional tests with MMT8

Mingazzini test vs MMT8 (strong correlation)
r = 0.762, p = 0.002

Test selection by shared decision-making

Modified Barré test chosen for upper extremity
All patients
Mingazzini test chosen for lower extremity
60.7%

Recording method and ePRO adherence · 12 weeks

Preferred app-based recording
82.1%
Weekly electronic patient-reported outcomes (ePROs) completed, mean weeks out of 12
6.9 (57.5%)

Original publication

Toward digitally supported self-assessment of patients with idiopathic inflammatory myopathies. Arthritis Res Ther. Published 22 February 2025. doi:10.1186/s13075-025-03504-z

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