Sjögren's disease & overlap diseases
Patients’ recollection about the onset of Sjögren’s disease – a mixed methods study on the patients’ perspective
Authors' conclusion
We describe patients' recollection of the onset of SjD.
Study context
- Population
- Sjögren's Disease (SjD) patients fulfilling the EULAR/ACR 2016 classification criteria31 qualitative, 103 cohort
- Participants
- 134 patients
- Exposure
- Qualitative part vs Independent
- Qualitative partn = 31
- Independentn = 103
- Outcome
- Patients' recollection of initial events and first symptoms of SjD
Methodological detailssemi-structured interviews, inductive thematic analysis, checklist verification in independent cohort
- Semi-structured interviews
- Inductive thematic analysis
- Checklist verification in independent cohort
Main finding
As reported in the abstract
Symptoms before diagnosis (independent cohort)
Dryness (main symptom)
n = 77, 74.8%
Migratory joint pain
n = 51, 49.5%
Fatigue
n = 47, 45.6%
Swelling/inflammation of parotid gland at onset
38.8%
n = 40
Observational data: associations, not effects.
Further findings
Qualitative themes of onset
- "Classic" SjD symptoms (fatigue, pain, dryness)
- Sicca symptoms started after initial swelling of parotid and/or lymph nodes
- Onset after hormonal transition or infections
Original publication
Patients’ recollection about the onset of Sjögren’s disease – a mixed methods study on the patients’ perspective. Arthritis Res Ther. Published 28 September 2024. doi:10.
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