Osteoporosis & bone health

Patient Self-Assessment of Walking Ability and Fracture Risk in Older Australian Adults

JAMA Netw OpenPublished Prospective cohort study

An erratum to this article was published (JAMA Netw Open, 5 Feb 2024 ↗)

Authors' conclusion

In this cohort study of 238 969 participants, self-reported walking limitations were associated with increased risk of fracture.

Study context

Population
Participants of the population-based Sax Institute 45 and Up Study (Australia), recruited 2005–2008 and followed for 5 years; 126,015 (53%) women, mean (SD) age 63 (11) years, and 112,954 (47%) men, mean (SD) age 61 (11) yearsof 266,912 enrolled
Participants
238,969 participants
Exposure
A little or a lot of self-reported walking limitation at 1000 m vs no limitation
Outcome
Incident fracture
Follow-up
5 years
Methodological detailspopulation-based, adjusted for age, falls, prior fractures and weight, Data analysis July 2020 to September 2023
  • Population-based
  • Adjusted for age, falls, prior fractures and weight
  • Data analysis July 2020 to September 2023

Main finding

As reported in the abstract

Incident fracture, by sex · mean (SD) follow-up 4.1 (0.8) years
Each group vs no limitationHazard ratio (95% CI)
Little limitationwomen
1.32(1.23–1.41)
Little limitationmen
1.46(1.34–1.60)
Lot of limitationwomen
1.60(1.49–1.71)
Lot of limitationmen
2.03(1.86–2.22)
Women with an incident fracture
7190
Men with an incident fracture
4267
Participants reporting a degree of walking limitation at baseline
≈20%
Women reporting a degree of walking limitation
39 324 [24%]
Men reporting a degree of walking limitation
23 191 [21%]
Fractures attributable to walking limitation
≈60%

Observational data: associations, not effects.

Further findings

Site-specific fractures (hip, vertebral, NHNV)

Association significant for hip, vertebral and NHNV fracture; increase in risk ranged from 21% to greater than 219%

Original publication

Patient Self-Assessment of Walking Ability and Fracture Risk in Older Australian Adults. JAMA Netw Open. Published 2 January 2024. doi:10.1001/jamanetworkopen.2023.52675

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.