Paediatric non-infectious granulomatous uveitis: a retrospective cohort study
Authors' conclusion
The cases of PGU were mostly idiopathic and had a high rate of complications.
Study context
- Population
- Children with non-infectious paediatric granulomatous uveitis before age 16 years, Paediatric Rheumatology Unit, Bicêtre Hospital, France, 2001–202390 affected eyes
- Participants
- 50 children
- Outcome
- Demographics, aetiologies, complications, treatments and visual prognosis
Methodological detailsretrospective chart review, single-centre
- Retrospective chart review
- Single-centre
Main finding
As reported in the abstract
- Idiopathic uveitis
- 29
- Sarcoidosis
- 15
- JIA
- 5
- Vogt-Koyanagi-Harada disease
- 1
- Median age at diagnosis, years (range)
- 9.8 (7.2-12.5)
- M:F sex ratio
- 0.52
- Panuveitis
- 56%
- Bilateral
- 84%
- Chronic
- 84%
- Uveomeningitis
- 12%
- Ocular complications at diagnosis (eyes)
- 68 of 90 eyes (76%)
- Systemic CSs
- 72%
- MTX
- 80%
- Eyes in remission at last follow-up
- 23%
- Eyes inactive at last follow-up
- 68%
- Eyes active at last follow-up
- 4%
- Median duration of follow-up, years
- 5.8
Observational data: associations, not effects.
Original publication
Paediatric non-infectious granulomatous uveitis: a retrospective cohort study. Rheumatology (Oxford). Published 6 May 2024. doi:10.
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