Relationship between ocular manifestations, laboratory findings, echocardiographic findings, and intravenous immunoglobulin resistance in Kawasaki disease
Authors' conclusion
Uveitis in KD is significantly associated with coronary artery dilatation, IVIG resistance, higher WBC count, platelet count, and CRP level.
Study context
- Population
- Kawasaki disease (KD) patients examined in the acute phase before treatment, June 2021 to March 2023
- Participants
- 58 patients
- Exposure
- KD with ocular involvement vs without involvement
- Outcome
- Incidence of ocular involvement in KD
- Follow-up
- Acute phase before treatment
Main finding
As reported in the abstract
Incidence of ocular involvement
Bilateral acute conjunctivitis
70.7%
Acute uveitis
30%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Coronary artery dilatation, IVIG resistance, mean WBC, platelet and CRP: uveitis vs no uveitisSignificantly higher rates and mean levels with uveitis | P < 0.05 |
| ESR, AST, ALT and uveitisNo significant relationships | P > 0.05 |
Age: uveitis vs no uveitis
- Age of patients with uveitis lower than those without
Examined items and acute bilateral conjunctivitis
- No significant correlations with any examined item
Original publication
Relationship between ocular manifestations, laboratory findings, echocardiographic findings, and intravenous immunoglobulin resistance in Kawasaki disease. Pediatr Rheumatol Online J. Published 1 May 2024. doi:10.
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