Systemic sclerosis & Raynaud's
Outcome measures used to assess gastrointestinal tract involvement in adults and children with systemic sclerosis: a scoping review
Authors' conclusion
We identified a wide array of outcome measures used to assess GI tract involvement in SSc with a paucity of longitudinal and paediatric data. Objective measures of GI tract function correlated poorly with symptoms and PROs
Study context
- Population
- Studies of gastrointestinal (GI) outcome measures in adults and children with systemic sclerosis (SSc), 1994–2024159 studies
- Outcome
- GI outcome measures used in SSc
Main finding
As reported in the abstract
- Outcome measures identified (oropharyngeal, oesophageal, gastric, small intestinal, colorectal, nutritional and/or patient-reported GI domains)
- 25
- Observational studies
- 150/159
- Studies of the oesophagus (most-studied GI segment)
- 97/159
- Studies reporting oesophageal manometry (most common measure)
- 56
- Studies reporting UCLA GIT 2.0 (most frequent patient-reported outcome (PRO))
- 34
- Studies with paediatric-specific outcome data
- 2
Original publication
Outcome measures used to assess gastrointestinal tract involvement in adults and children with systemic sclerosis: a scoping review. Clin Exp Rheumatol. Published 4 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →