Opioid use in children with inflammatory bowel disease-related arthritis
Authors' conclusion
Chronic opioid use in adolescents with IBD-related arthritis was higher than that of total IBD cohort but stable over the years of study.
Study context
- Population
- Adolescents <18 years with IBD (incl. IBD-related arthritis), ≥1 year continuous enrolment and ≥1 pharmacy claim, Truven Health MarketScan database
- Participants
- 480 vs 14,943
- Exposure
- IBD-related arthritis vs total IBD cohort
- IBD-related arthritisn = 480
- Total IBDn = 14,943reference
- Outcome
- Chronic opioid exposure
Methodological detailsclaims database (Truven Health MarketScan), multivariable logistic regression
- Claims database (Truven Health MarketScan)
- Multivariable logistic regression
Main finding
As reported in the abstract
Chronic opioid use
Observational data: associations, not effects.
Further findings
Factors associated with chronic opioid exposure in IBD
- Joint pain and arthritis significantly associated with chronic opioid exposure (multivariable regression)
Factors associated with chronic opioid use in IBD-related arthritis
- Older age, public insurance, gastrointestinal surgery, hospitalisation and psychiatric comorbidities significantly associated with chronic opioid use
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Opioid use in children with inflammatory bowel disease-related arthritis. Clin Exp Rheumatol. Published 10 November 2022. doi:10.
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