Pediatric rheumatology

Modified Juvenile Spondyloarthritis Disease Activity Index in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry

J RheumatolPublished Validation study

Authors' conclusion

We propose the term modified JSpADA for the modification of JSpADA with 6 elements (JSpADA6-no Schober, no CRP/ESR).

Study context

Population
North American patients with enthesitis-related arthritis (ERA), CARRA Registry; mean age 13.7 years, disease duration 30.9 months
Participants
51 patients64 visits
Comparison
JSpADA vs modified versions
Outcome
Correlation (r) with cJADAS10, PGA and CHAQ
Methodological detailsregistry-based, OMERACT principles: face validity, discriminative validity, responsiveness to change
  • Registry-based
  • OMERACT principles: face validity, discriminative validity, responsiveness to change

Performance

As reported in the abstract

Test or modelR with cJADAS10R with physician global assessment (PGA)R with CHAQ
JSpADA0.810.690.22
JSpADA7-no Schober0.810.650.35
JSpADA7-no CRP/ESR0.790.670.34
JSpADA6-no Schober, no CRP/ESR0.800.640.39

R with cJADAS10

JSpADA0.81
JSpADA7-no Schober0.81
JSpADA7-no CRP/ESR0.79
JSpADA6-no Schober, no CRP/ESR0.80

R with physician global assessment (PGA)

JSpADA0.69
JSpADA7-no Schober0.65
JSpADA7-no CRP/ESR0.67
JSpADA6-no Schober, no CRP/ESR0.64

R with CHAQ

JSpADA0.22
JSpADA7-no Schober0.35
JSpADA7-no CRP/ESR0.34
JSpADA6-no Schober, no CRP/ESR0.39

Original publication

Modified Juvenile Spondyloarthritis Disease Activity Index in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. J Rheumatol. Published 1 November 2022. doi:10.3899/jrheum.220509

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