Sjögren's disease & overlap diseases

Obesity in primary Sjögren's disease

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

According to BMI, at least 20% of patients were obese, this prevalence increased to 40% when BIA was used, with a higher prevalence found in central obesity. Obesity did not impact the symptoms and disease activity but might be associated with damage.

Study context

Population
Patients with primary Sjögren's disease (SjD)
Participants
91 patients
Exposure
Obese vs non-obese patients
  • Obesen = 18
Outcome
Prevalence of obesity

Main finding

As reported in the abstract

Prevalence of obesity by definition

Obese according to body mass index (BMI)

18

19.7%

Obese according to waist circumference (WC)

33

36.2%

Obese according to waist-to-hip ratio (WHR)

48

52.7%

Obese according to fat mass index (FMI)

37

40.6%

Observational data: associations, not effects.

Further findings

Anti-Ro/SSA antibodies, obese vs non-obese by BMI

Obese group had a higher prevalence of anti-Ro/SSA antibodies

SSDDI and obesity by WC, WHR and FMI definitions

Multivariate analysis showed an association between SSDDI and obesity

Original publication

Obesity in primary Sjögren's disease. Clin Exp Rheumatol. Published 19 June 2025. doi:10.55563/clinexprheumatol/9d0mr2

Composed by AI from the published abstract and checked against it. How Briefs are made →

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