Sjögren's disease & overlap diseases

The Novel OMERACT Ultrasound Scoring System for Salivary Gland Changes in Patients With Sjögren Syndrome Is Associated With Magnetic Resonance Imaging (MRI) and Salivary Flow Rates

J RheumatolPublished Cross-sectional study

Authors' conclusion

There is moderate to strong agreement between the OMERACT US and MRI scores for major salivary glands in patients with pSS.

Study context

Population
Patients with pSS who also had MRIs performed
Participants
11 patients
Exposure
OMERACT ultrasound (US) scoring vs MRI scoring and unstimulated whole salivary flow rates (U-WSFRs)
Outcome
Agreement between OMERACT US and MRI scores (score ≥ 2 = gland pathology), and association between U-WSFRs and imaging structural lesions
Methodological detailsconstruct validity, semiquantitative 0-3 scoring, nine sonographers, 2 radiologists
  • Construct validity
  • Semiquantitative 0-3 scoring
  • Nine sonographers
  • 2 radiologists

Main finding

As reported in the abstract

Right PG agreement

73-91%

median 82%

Left PG agreement

73-91%

median 91%

Right SMG agreement

55-91%

median 55%

Left SMG agreement

55-82%

median 55%

Observational data: associations, not effects.

Further findings

Prevalence of morphological lesions (score ≥ 2) · value shown is for PGs

PGs

SMGs

Agreement between hyposalivation and US score ≥ 2

Both PGs
91-100% (median 83%)
Both submandibular glands (SMGs)
55-91% (median 67%)

Original publication

The Novel OMERACT Ultrasound Scoring System for Salivary Gland Changes in Patients With Sjögren Syndrome Is Associated With MRI and Salivary Flow Rates. J Rheumatol. Published 1 November 2023. doi:10.3899/jrheum.2023-0202

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